先引用Mcrsoft DAO 3.6(或2.5或3.51) Object Library和Mcrsoft Access 9.0 Object Library，在Form上加个Command1,粘贴以下代码：

Private Sub Command1_Click()
   Dim wrkDefault As Workspace
   Dim dbsNew As Database
   Dim tdfNew As TableDef
   Dim NewDB As Database

   If Dir("D:\NewDB.mdb") <> "" Then Kill "D:\NewDB.mdb"
   '{取当前目录的话去掉路径： If Dir("NewDB.mdb") <> "" Then Kill "NewDB.mdb")}
   Set wrkDefault = DBEngine.Workspaces(0)
   Set dbsNew = wrkDefault.CreateDatabase("d:\NewDB.mdb", dbLangGeneral, dbEncrypt)
   '{取当前目录的话去掉路径： Set dbsNew = wrkDefault.CreateDatabase("NewDB.mdb", dbLangGeneral, dbEncrypt)}

dbsNew.NewPassword "", "123" '设置数据库密码为123
  
  
   Set wrkDefault = Nothing
   Set dbsNew = Nothing

End Sub